Evidence-Based Medicine

Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice (print only)

EvidenceUpdates (McMaster University & DynaMed Plus, requires free registration)

BMJ Best Practice EBM Toolkit

American Family Physician EBM Toolkit

Anthony Crocco, McMaster University, Sketchy EBM, How I Read a Paper! https://youtu.be/eSEP2T-xz8g

Terry Shaneyfelt, University of Alabama School of Medicine at UAB

Approach to Reading a Clinical Research Study

How to Critically Appraise a Diagnostic Test Study 

How to Critically Appraise a Harm Study: Part 1

How to Critically Appraise a Harm Study: Part 2

How to Critically Appraise a Prognosis Study

How to Critically Appraise a Therapy Study: Part 1

How to Critically Appraise a Therapy Study: Part 2

A Series from the Canadian Medical Association Journal

1. Relative risk reduction, absolute risk reduction and number needed to treat
CMAJ. 2004 Aug 17;171(4):353-358.

2. Measures of precision (confidence intervals)
CMAJ. 2004 Sep 14;171(6):611-615.

3. Measures of observer variability (kappa statistic)
CMAJ. 2004 Nov 23;171(11):1369-1373.

4. Assessing heterogeneity of primary studies in systematic reviews and whether to combine their results
CMAJ. 2005 March 1;172(5):661-665.

5. The effect of spectrum of disease on the performance of diagnostic tests
CMAJ. 2005 March 1;172(5):661-665.

Greenhalgh, Trisha. How to Read a Paper: The Basics of Evidence-Based Medicine. 5th ed., John Wiley & Sons, Incorporated, 2014. 

Articles by Professor Trisha Greenhalgh of University College London
  

The Medline database.
BMJ. 1997 Jul 19;315(7101):180-3.

Getting your bearings (deciding what the paper is about).
BMJ. 1997 Jul 26;315(7102):243-6.

Assessing the methodological quality of published papers.
BMJ. 1997 Aug 2;315(7103):305-8.

Statistics for the non-statistician. I: Different types of data need different statistical tests.
BMJ. 1997 Aug 9;315(7104):364-6.
Erratum in: BMJ 1997 Sep 13;315(7109):675.

Statistics for the non-statistician. II: "Significant" relations and their pitfalls.
BMJ. 1997 Aug 16;315(7105):422-5.

Papers that report drug trials.
BMJ. 1997 Aug 23;315(7106):480-3.

Papers that report diagnostic or screening tests.
BMJ. 1997 Aug 30;315(7107):540-3.
Erratum in: BMJ 1997 Oct 11;315(7113):942.
Erratum in: BMJ 1998 Jan 17;316(7126):225.

Papers that tell you what things cost (economic analyses).
BMJ. 1997 Sep 6;315(7108):596-9.

Papers that summarise other papers (systematic reviews and meta-analyses).
BMJ. 1997 Sep 13;315(7109):672-5.

Papers that go beyond numbers (qualitative research).
BMJ. 1997 Sep 20;315(7110):740-3.